[HTML][HTML] … receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells

Y Lin, K Higashisaka, T Shintani, A Maki… - Scientific reports, 2020 - nature.com
… Given that these pathways promote acquired EGFR-TKI resistance 22,23 , we hypothesized
… the Wnt/β-catenin and NF-κB pathways in acquired erlotinib resistance in PC9 cells. Here, …

Progesterone receptor membrane component 1 and its accomplice: Emerging therapeutic targets in lung cancer

S Solairaja, S Ramalingam, NR Dunna… - … Metabolic & Immune …, 2022 - ingentaconnect.com
… nexus between Wnt/β-catenin and NF-κB pathways [42], (Table 1). … Progesterone
receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin

Progesterone receptor membrane component 2 expression leads to erlotinib resistance in lung adenocarcinoma cells

S Hanamuro, Y Lin, H Konishi… - Die Pharmazie-An …, 2021 - ingentaconnect.com
components of the PGRMC1 and PGRMC2 signal transduction pathways such as NF-κB
signaling and Wnt/β-catenin … to erlotinib resistance, initiating crosstalk of Wnt/beta-catenin and …

Beyond Hormones: Investigating the Impact of Progesterone Receptor Membrane Component 1 in Lung Adenocarcinoma

S Solairaja, S Venkatabalasubramanian - The Journal of Membrane …, 2024 - Springer
crosstalk between the WNT/β-catenin and NF-κB pathways leading to erlotinib resistance. …
the maintenance of tumour-initiating cells (cancer stem cells) and WNT downstream targets …

[HTML][HTML] Anti-cancer therapeutic strategies based on HGF/MET, EpCAM, and tumor-stromal cross talk

K Barzaman, R Vafaei, M Samadi, MH Kazemi… - Cancer Cell …, 2022 - Springer
cancer cells, studies suggest more cross talk between NF-κB … C-Met and Wnt-β-catenin
signaling pathways mainly … -Ras affect resistance to treatment with gefitinib or erlotinib drugs [135]…

A time for YAP1: Tumorigenesis, immunosuppression and targeted therapy

M Shibata, K Ham, MO Hoque - International journal of cancer, 2018 - Wiley Online Library
… and has crosstalk with other cancer promoting pathways. … However, other pathways such
as Wnt/β-catenin pathway is … For example, the transcription factors NF-κB and STAT3 promote …

[HTML][HTML] Progestins as anticancer drugs and chemosensitizers, new targets and applications

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Pharmaceutics, 2021 - mdpi.com
… The cross-talk of the Wnt/β-catenin signaling pathway with … EGFR, leading to the activation
of the Wnt/β-catenin and NF-κB … to anticancer drugs-protein kinase inhibitors such as erlotinib

Niclosamide: Beyond an antihelminthic drug

W Chen, RA Mook Jr, RT Premont, J Wang - Cellular signalling, 2018 - Elsevier
Wnt/β-catenin, mTORC1, STAT3, NF-κB and Notch signaling … of the estrogen and progesterone
receptors and the lack of … erlotinib potently repressed growth of erlotinib-resistant lung

[HTML][HTML] The therapeutic role of PNU-74654 in hepatocellular carcinoma may involve suppression of NF-κB signaling

MY Wu, CC Wang, YC Chang, CY Yu, WW Sung… - Medicina, 2022 - mdpi.com
… The Wnt/β-catenin pathway is correlated with tumor cellcomponent 1 conferred resistance
to EGFR-targeted therapy … due to interference with cell cycle regulation and the NF-κB

Wnt/β-catenin Signaling in Lung Cancer: Association with Proliferation, Metastasis, and Therapy Resistance

M Entezari, M Deldar Abad Paskeh… - Current Cancer Drug …, 2024 - ingentaconnect.com
… -promoting factor increases erlotinib cytotoxicity. Based on the … mediates crosstalk of Wnt
and NF-κB to increase cancerProgesterone receptor membrane component 1 leads to …